General Information:

Id: 1,963 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Rattus norvegicus
male
article
Reference: Koves TR et al.(2008) Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. Cell Metab. 7: 45-56 [PMID: 18177724]

Interaction Information:

Comment Under fasting conditions, serum acylcarnitines were similar between the two diet groups. Conversely, serum samples collected in the fed state revealed higher levels of several fatty acid-derived species and reduced levels of C3, C4, and C5 in HF-fed animals compared to SC-fed animals.
Formal Description
Interaction-ID: 15401

environment

high-fat diet

increases_activity of

process

fatty acid beta-oxidation