General Information:

Id: 1,954
Diseases: Alzheimer disease - [OMIM]
Mammalia
review
Reference: Geldmacher DS(2010) Alzheimer disease prevention: focus on cardiovascular risk, not amyloid Cleve Clin J Med 77: 689-704 [PMID: 20889807]

Interaction Information:

Comment Common cardiovascular comorbidities are associated with increased risk for Alzheimer disease.
Formal Description
Interaction-ID: 15140

increases_activity of

Comment The risk of Alzheimer disease is lower with a diet high in antioxidants and polyunsaturated fatty acids.
Formal Description
Interaction-ID: 15141

environment

antioxidant diet

decreases_activity of

Comment The risk of Alzheimer disease is lower with a diet high in antioxidants and polyunsaturated fatty acids.
Formal Description
Interaction-ID: 15146

environment

polyunsaturated fatty acid diet

decreases_activity of

Comment Physical activity in midlife and in late life was associated with a lower risk of Alzheimer disease in observational studies.
Formal Description
Interaction-ID: 15147

environment

exercise

decreases_activity of

(physical activity in midlife and in late life)
Comment Alzheimer disease was also found to be associated with diabetes.
Formal Description
Interaction-ID: 15148

cooccurs with

disease

Diabetes mellitus

Comment Patients who regularly take nonsteroidal antiinflammatory drugs (NSAIDs) or steroids for chronic, systemic inflammatory diseases (eg, arthritis) have a 45% to 60% reduced risk for Alzheimer disease.
Formal Description
Interaction-ID: 15149

drug/chemical compound

NSAID

decreases_activity of

Comment Patients who regularly take nonsteroidal antiinflammatory drugs (NSAIDs) or steroids for chronic, systemic inflammatory diseases (eg, arthritis) have a 45% to 60% reduced risk for Alzheimer disease.
Formal Description
Interaction-ID: 15151

drug/chemical compound

Antiinflammatory agent

decreases_activity of