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Diseases	Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	1,953 (click here to show other Interactions for entry)
Diseases:	Alzheimer disease - [OMIM]
Organism:	Mus musculus
Organism Model:	Tg2576 mouse
Publication type:	article
Reference:	Chiba T et al.(2009) Amyloid-beta causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons. Mol. Psychiatry 14: 206-222 [PMID: 18813209]

Interaction Information:

Comment	p-STAT3 levels in hippocampal neurons age-dependently decreased in both AD model mice and AD patients.
Formal Description Interaction-ID: 15137	process aging decreases_quantity of protein modification STAT3-phos in hippocampal neurons; in AD mouse model and AD patients

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