General Information:

Id: 1,913 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mus musculus
male
article
Reference: Hosoi T et al.Myeloid differentiation factor 88 (MyD88)-deficiency increases risk of diabetes in mice [PMID: 20824098]

Interaction Information:

Comment The increase of the cholesterol (total, free and esterified cholesterol) levels was markedly higher in MyD88-deficient mice fed the HFD, compared to normal HFD-fed mice.
Formal Description
Interaction-ID: 14678

environment

high-fat diet

increases_quantity of

drug/chemical compound

Cholesterol

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Comment The increase of the cholesterol (total, free and esterified cholesterol) levels was markedly higher in MyD88-deficient mice fed the HFD, compared to normal HFD-fed mice.
Formal Description
Interaction-ID: 14679

gene/protein

MYD88

affects_quantity of

drug/chemical compound

Cholesterol

after high-fat diet
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