General Information:

Id: 1,912 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mus musculus
article
Reference: Kleinridders A et al.(2009) MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity. Cell Metab. 10: 249-259 [PMID: 19808018]

Interaction Information:

Comment Analysis of blood glucose and plasma insulin concentrations, as well as glucose and insulin tolerance tests, revealed unaltered glucose metabolism in mice deficient for the TLR adaptor molecule MyD88 in the CNS (MyD88(DeltaCNS)) compared to control mice.
Formal Description
Interaction-ID: 14653

gene/protein

MYD88

NOT affects_activity of

process

glucose metabolic process

in central nervous system