General Information:

Id: 1,888 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mammalia
review
Reference: Chung JH et al.(2008) Molecular mechanism of PPAR in the regulation of age-related inflammation Ageing Res. Rev. 7: 126-136 [PMID: 18313368]

Interaction Information:

Comment In support of the involvement of PPAR-gamma in Alzheimer disease, people with long-term intake of PPAR-gamma ligand, certain NSAIDs (Non-steroid antiinflammatory drugs e.g., ibuprofen, indomethacin, naproxen) exhibit reduced risk and manifest delayed development of Alzheimer disease.
Formal Description
Interaction-ID: 14406

drug/chemical compound

Ibuprofen

decreases_activity of

Drugbank entries Show/Hide entries for Ibuprofen