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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	1,884 (click here to show other Interactions for entry)
Diseases:	Alzheimer disease - [OMIM]
Organism:	Mammalia
Publication type:	review
Reference:	Chung HY et al.(2009) Molecular inflammation: underpinnings of aging and age-related diseases. Ageing Res. Rev. 8: 18-30 [PMID: 18692159]

Interaction Information:

Comment	The immune system is dysregulated with age.
Formal Description Interaction-ID: 14305	process aging decreases_activity of process immune system process

Comment	Aging alters the redox status.
Formal Description Interaction-ID: 14306	process aging affects_activity of process cell redox homeostasis

Comment	Overproduced and unregulated RS during aging are a major causative factor in the activation of immune systems as exemplified in over-reactive macrophages in the inflammatory process.
Formal Description Interaction-ID: 14315	process aging increases_quantity of drug/chemical compound Reactive oxygen species

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