CIDeRGeneral Information:
| Id: | 1,884 |
| Diseases: |
Alzheimer disease
- [OMIM]
|
| Mammalia | |
| review | |
| Reference: | Chung HY et al.(2009) Molecular inflammation: underpinnings of aging and age-related diseases. Ageing Res. Rev. 8: 18-30 [PMID: 18692159] |
Interaction Information:
| Comment | The immune system is dysregulated with age. |
|
Formal Description Interaction-ID: 14305 |
|
| Comment | Aging alters the redox status. |
|
Formal Description Interaction-ID: 14306 |
|
| Comment | Dysregulation of the immune system with age and altered redox status during aging lead to increases in systemic inflammatory status due to the activation of a wide variety of inflammatory mediators through mainly oxidative stress-induced redox imbalance. |
|
Formal Description Interaction-ID: 14307 |
|
| Comment | Dysregulation of the immune system with age and altered redox status during aging lead to increases in systemic inflammatory status due to the activation of a wide variety of inflammatory mediators through mainly oxidative stress-induced redox imbalance. |
|
Formal Description Interaction-ID: 14311 |
|
| Comment | Overproduced and unregulated RS during aging are a major causative factor in the activation of immune systems as exemplified in over-reactive macrophages in the inflammatory process. |
|
Formal Description Interaction-ID: 14315 |
|
| Comment | Overproduced and unregulated RS during aging are a major causative factor in the activation of immune systems as exemplified in over-reactive macrophages in the inflammatory process. |
|
Formal Description Interaction-ID: 14318 |
|
| Comment | Overproduced and unregulated RS during aging are a major causative factor in the activation of immune systems as exemplified in over-reactive macrophages in the inflammatory process. |
|
Formal Description Interaction-ID: 14320 |
|