General Information:

Id: 1,863 (click here to show other Interactions for entry)
Diseases: MERRF - [OMIM]
Homo sapiens
BTO:0001255 skin fibroblast
article
Reference: Wu SB et al.(2010) Mitochondrial DNA mutation-elicited oxidative stress, oxidative damage, and altered gene expression in cultured cells of patients with MERRF syndrome. Mol. Neurobiol. 41: 256-266 [PMID: 20411357]

Interaction Information:

Comment The up-regulation of MMP-1 was apparently induced by the increased production of ROS in affected cells because the same change could be observed by treatment of the cells with H2O2.
Formal Description
Interaction-ID: 14245

drug/chemical compound

H2O2

increases_quantity of

gene/protein

MMP1

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