General Information:

Id: 179 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mus musculus
ob/ob mouse with GPAT1 knockdown
article
Reference: Xu H et al.(2006) Hepatic knockdown of mitochondrial GPAT1 in ob/ob mice improves metabolic profile Biochem. Biophys. Res. Commun. 349: 439-448 [PMID: 16935266]

Interaction Information:

Comment Knockdown of hepatic mitochondrial GPAT1 in ob/ob mice resulted in reduced hepatic triacylglycerol, diacylglycerol, and free fatty acids, as well as reduced plasma cholesterol and plasma glucose.
Formal Description
Interaction-ID: 12329

gene/protein

GPAM

affects_quantity of

drug/chemical compound

Cholesterol

in blood; in ob/ob mice
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