General Information:

Id: 1,759 (click here to show other Interactions for entry)
Diseases: Neurological
Mus musculus
article
Reference: Ichi S et al.(2011) Role of Pax3 acetylation in the regulation of Hes1 and Neurog2 Mol. Biol. Cell 22: 503-512 [PMID: 21169561]

Interaction Information:

Comment Chromatin immunoprecipitation assays showed that SIRT1 is associated with Hes1 and Neurog2 promoters during murine embryonic caudal neural tube development at E9.5, but not at E12.5. Over-expression of SIRT1 decreased Pax3 acetylation, Neurog2 and Brn3a positive staining.
Formal Description
Interaction-ID: 13222

gene/protein

SIRT1

affects_activity of

gene/protein

NEUROG2

during murine embryonic caudal neural tube development at E9.5, but not at E12.5