General Information:

Id: 1,709 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
SOD1G37R transgenic mouse, transfected with human SOD1G37R
BTO:0001279 spinal cord
article
Reference: Jeong SY et al.(2009) Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis J. Neurosci. 29: 610-619 [PMID: 19158288]

Interaction Information:

Comment Quantification of the amount of total iron in spinal cord samples taken from 12-month-old mice a showed a 56% increase in SOD1G37R mice compared with age-matched wild-type controls.
Formal Description
Interaction-ID: 12856

gene/protein mutant

SOD1-p.G37R

increases_quantity of

drug/chemical compound

Iron

at the age of 12 months