CIDeRGeneral Information:
| Id: | 1,664 (click here to show other Interactions for entry) |
| Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance Obesity - [OMIM] |
| Mus musculus | |
| article | |
| Reference: | Hirosumi J et al.(2002) A central role for JNK in obesity and insulin resistance Nature 420: 333-336 [PMID: 12447443] |
Interaction Information:
| Comment | An absence of JNK1 results in decreased adiposity, significantly improved insulin sensitivity and enhanced insulin receptor signalling capacity in two different models of mouse obesity. |
|
Formal Description Interaction-ID: 12248 |
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| Drugbank entries | Show/Hide entries for MAPK8 |