General Information:

Id: 1,633 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Rattus norvegicus
mitochondria
article
Reference: Hansson CA et al.(2004) Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria J. Biol. Chem. 279 [PMID: 15456764]

Interaction Information:

Comment Nicastrin, presenilin (1 or 2), APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria.
Formal Description
Interaction-ID: 11974

gene/protein

PSEN1

is_part_of

complex/PPI

Gamma-secretase complex