General Information:

Id: 1,627 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
article
Reference: Hill JW et al.(2008) Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice J. Clin. Invest. 118: 1796-1805 [PMID: 18382766]

Interaction Information:

Comment Targeted POMC PI3K deletion disrupts insulin and leptin effects on neuronal activity.
Formal Description
Interaction-ID: 11919

complex/PPI

Phosphatidylinositol 3-kinase

affects_activity of

in POMC neurons