General Information:

Id: 1,610 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
Reference: Birsoy K et al.(2008) Cellular program controlling the recovery of adipose tissue mass: An in vivo imaging approach Proc. Natl. Acad. Sci. U.S.A. 105 [PMID: 18753616]

Interaction Information:

Comment Acute leptin deficiency repressed carnitine-palmitoyl transferase-I (CPT-I) and peroxisomal acyl-CoA oxidase (ACO), both of which are required for fatty acid oxidation and white adipose phosphoenolpyruvate carboxykinase mRNA, which would detract from acetyl-CoA accumulation.
Formal Description
Interaction-ID: 11853

decreases_activity of