General Information:

Id: 156 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Homo sapiens
BTO:0000793 SH-SY5Y cell
article
Reference: Dagda RK et al.(2009) Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission. J. Biol. Chem. 284 [PMID: 19279012]

Interaction Information:

Comment Transient expression of Parkin significantly reversed cell death induced by loss of PINK1.
Formal Description
Interaction-ID: 2626

gene/protein

PRKN

decreases_activity of

process

neuron death

if cell death has been induced by loss of PINK1
Comment Transient expression of Parkin significantly reversed cell death induced by loss of PINK1.
Formal Description
Interaction-ID: 2653

gene/protein

PRKN

affects_activity of

gene/protein

PINK1