General Information:

Id: 1,548 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Homo sapiens
BTO:0000793 SH-SY5Y cell; BTO:0001370 THP-1 cell
Reference: Lee M et al.(2011) Mg2+ ions reduce microglial and THP-1 cell neurotoxicity by inhibiting Ca2+ entry through purinergic channels Brain Res. 1369: 21-35 [PMID: 21040713]

Interaction Information:

Comment Mg2+ decreases the rapid rise in intracellular calcium induced by activation of purinergic receptors.
Formal Description
Interaction-ID: 11071

drug/chemical compound


decreases_quantity of

drug/chemical compound


in microglia cells