General Information:

Id: 1,548 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Homo sapiens
BTO:0000793 SH-SY5Y cell; BTO:0001370 THP-1 cell
article
Reference: Lee M et al.(2011) Mg2+ ions reduce microglial and THP-1 cell neurotoxicity by inhibiting Ca2+ entry through purinergic channels Brain Res. 1369: 21-35 [PMID: 21040713]

Interaction Information:

Comment Ca(2+) influx into microglia and THP-1 cells following activation of purinergic receptors induces inflammation.
Formal Description
Interaction-ID: 11069

increases_quantity of

drug/chemical compound

Ca2+

in microglia cells