General Information:

Id: 1,547 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Homo sapiens
BTO:0000143 substantia nigra
article
Reference: Zheng B et al.(2010) PGC-1alpha, a potential therapeutic target for early intervention in Parkinsons disease Sci Transl Med 2: 52RA73 [PMID: 20926834]

Interaction Information:

Comment Overexpression of PGC-1alpha coactivated the expression of nuclear-encoded subunits of complex I, II, III, IV, and V of the mitochondrial ETC.
Formal Description
Interaction-ID: 11058

gene/protein

PPARGC1A

increases_activity of

complex/PPI

Mitochondrial respiratory chain