General Information:

Id: 1,547 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Homo sapiens
BTO:0000143 substantia nigra
article
Reference: Zheng B et al.(2010) PGC-1alpha, a potential therapeutic target for early intervention in Parkinsons disease Sci Transl Med 2: 52RA73 [PMID: 20926834]

Interaction Information:

Comment PGC-1alpha overexpression suppresses dopaminergic neuron loss induced by A53T-synuclein and rotenone.
Formal Description
Interaction-ID: 11056

gene/protein

PPARGC1A

decreases_activity of

gene/protein mutant

SNCA-p.A53T

if neuron death has been induced by SNCA-A53T