General Information:

Id: 1,540 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Parkinson disease 7, autosomal recessive early-onset - [OMIM]
Mammalia
article/cited
Reference: Choi DH et al.(2011) DJ-1 cleavage by matrix metalloproteinase 3 mediates oxidative stress-induced dopaminergic cell death Antioxid. Redox Signal. 14: 2137-2150 [PMID: 20969476]

Interaction Information:

Comment DJ-1 works as an atypical peroxiredoxin-like peroxidase that scavenges H2O2. DJ-1 knockout mice show a deficit in scavenging mitochondrial H2O2. (cited information)
Formal Description
Interaction-ID: 11001

gene/protein

PARK7

decreases_quantity of

drug/chemical compound

H2O2

Drugbank entries Show/Hide entries for PARK7