General Information:

Id: 1,539 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Mammalia
article/cited
Reference: Xu H et al.(2010) Rg1 protects iron-induced neurotoxicity through antioxidant and iron regulatory proteins in 6-OHDA-treated MES23.5 cells J. Cell. Biochem. 111: 1537-1545 [PMID: 20872781]

Interaction Information:

Comment There is increasing evidence that the onset of PD is associated with iron accumulation in substantia nigra pars compacta (SNpc) in parkinsonian brain. (cited information)
Formal Description
Interaction-ID: 10997

disease

Parkinson disease

increases_quantity of

drug/chemical compound

Iron

in substantia nigra