General Information:

Id: 1,538 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Mammalia
BTO:0004476 MES-23.5 cell
article
Reference: Xu H et al.(2010) Rg1 protects iron-induced neurotoxicity through antioxidant and iron regulatory proteins in 6-OHDA-treated MES23.5 cells J. Cell. Biochem. 111: 1537-1545 [PMID: 20872781]

Interaction Information:

Comment There was a 2.41-fold increase of DMT1+IRE mRNA in 6-OHDA treated cells. Pretreatment with Rg1 reversed the increase of DMT1+IRE mRNA.
Formal Description
Interaction-ID: 10982

drug/chemical compound

6-OHDA

increases_expression of

gene/protein

SLC11A2