General Information:

Id: 1,538 (click here to show other Interactions for entry)
Diseases: Parkinson disease
BTO:0004476 MES-23.5 cell
Reference: Xu H et al.(2010) Rg1 protects iron-induced neurotoxicity through antioxidant and iron regulatory proteins in 6-OHDA-treated MES23.5 cells J. Cell. Biochem. 111: 1537-1545 [PMID: 20872781]

Interaction Information:

Comment Iron treatment decreased the mitochondrial membrane potential. Rg1 pretreatment could restore the mitochondrial membrane potential to the control. This indicated Rg1 could protect iron-induced damage of dopamine neurons.
Formal Description
Interaction-ID: 10978

drug/chemical compound

Ginsenoside Rg1

decreases_activity of


neuron death

if neuron death has been induced by iron