General Information:

Id: 1,505 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Reference: Gomez FJ et al.(2011) Iron mediates neuritic tree collapse in mesencephalic neurons treated with 1-methyl-4-phenylpyridinium (MPP+) J Neural Transm 118: 421-431 [PMID: 20890618]

Interaction Information:

Comment GSH is the most abundant intracellular reductant in the central nervous system, where it acts as the main antioxidant agent. (cited information)
Formal Description
Interaction-ID: 10640

drug/chemical compound


decreases_activity of

in central nervous system
Drugbank entries Show/Hide entries for Glutathione
Comment Post-mortem studies revealed decreased levels of GSH in degenerating substantia nigra of PD patients. (cited information)
Formal Description
Interaction-ID: 10641


Parkinson disease

decreases_quantity of

drug/chemical compound


in substantia nigra
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