General Information:

Id: 148 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Homo sapiens
BTO:0000793 SH-SY5Y cell
article
Reference: Xiong H et al.(2009) Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation. J. Clin. Invest. 119: 650-660 [PMID: 19229105]

Interaction Information:

Comment Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex, called PPD complex, promoting ubiquitination and degradation of aberrantly expressed Parkin and Synphilin-1.
Formal Description
Interaction-ID: 548

complex/PPI

PPD complex

increases_ubiquitination/sumoylation of

gene/protein

PARK2