General Information:

Id: 1,455 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
male
article
Reference: Wu D et al.(2007) Aging up-regulates expression of inflammatory mediators in mouse adipose tissue J. Immunol. 179: 4829-4839 [PMID: 17878382]

Interaction Information:

Comment Epididymal adipose tissue from old lean mice have higher mRNA expression of IL-1beta, IL-6, TNF-alpha, and COX-2 and lower mRNA expression of PPAR-gamma, a nuclear receptor possessing antiinflammatory and insulin-sensitizing properties, compared with those from young lean mice.
Formal Description
Interaction-ID: 10270

process

aging

decreases_expression of

gene/protein

PPARG

in epididymal adipose tissue
Drugbank entries Show/Hide entries for PPARG