General Information:

Id: 1,441 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Hemochromatosis, type 1 - [OMIM]
Mammalia
review
Reference: Cahill CM et al.(2009) Amyloid precursor protein and alpha synuclein translation, implications for iron and inflammation in neurodegenerative diseases Biochim. Biophys. Acta 1790: 615-628 [PMID: 19166904]

Interaction Information:

Comment Brain autopsy samples from AD patients have elevated levels of ferritin iron, particularly in the neurons of the basal ganglia and most amyloid plaques contain iron and ferritin-rich cells.
Formal Description
Interaction-ID: 10351

drug/chemical compound

Iron

is localized in

phenotype

ferritin-rich cell

in AD patients