General Information:

Id: 1,439 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mus musculus
article
Reference: Netea MG et al.(2006) Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance Nat. Med. 12: 650-656 [PMID: 16732281]

Interaction Information:

Comment Il18-/- mice had increased cholesterol and triglyceride concentrations. The increased cholesterol concentration resulted largely from elevated high-density lipoprotein (HDL).
Formal Description
Interaction-ID: 10120

gene/protein

IL18

affects_quantity of

drug/chemical compound

Cholesterol

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