General Information:

Id: 1,422 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
review
Reference: Rogers JT et al.(2008) Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimers disease Biochem. Soc. Trans. 36: 1282-1287 [PMID: 19021541]

Interaction Information:

Comment Neurofibrillary tangles that are the second major hallmark of AD are negatively charged and capable of binding iron, which promotes further neurotoxicity during disease progression.
Formal Description
Interaction-ID: 9898

drug/chemical compound

Iron

interacts (colocalizes) with