General Information:

Id: 1,420 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mus musculus
APP-/- neurons
article
Reference: Duce JA et al.(2010) Iron-export ferroxidase activity of beta-amyloid precursor protein is inhibited by zinc in Alzheimers disease Cell 142: 857-867 [PMID: 20817278]

Interaction Information:

Comment APP in WT mice prevents iron accumulation and oxidative stress compared to APP-/- mice.
Formal Description
Interaction-ID: 12090

gene/protein

APP

NOT increases_quantity of

drug/chemical compound

Iron

Drugbank entries Show/Hide entries for APP