General Information:

Id: 1,418 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
BTO:0000007 HEK-293 cell
article
Reference: Duce JA et al.(2010) Iron-export ferroxidase activity of beta-amyloid precursor protein is inhibited by zinc in Alzheimers disease Cell 142: 857-867 [PMID: 20817278]

Interaction Information:

Comment The absence of the ferroxidase results in decreased iron release into the extracellular space, as Fe2+ is unable to be converted into Fe3+.
Formal Description
Interaction-ID: 9876

affects_quantity of

drug/chemical compound

Iron

in extracellular space