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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	1,409 (click here to show other Interactions for entry)
Diseases:	Diabetes mellitus, type II - [OMIM] Insulin resistance
Organism:	Homo sapiens
Publication type:	article
Reference:	Larsen CM et al.(2007) Interleukin-1-receptor antagonist in type 2 diabetes mellitus N. Engl. J. Med. 356: 1517-1526 [PMID: 17429083]

Interaction Information:

Comment	The blockade of interleukin-1 with anakinra improved glycemia and beta-cell secretory function and reduced markers of systemic inflammation.
Formal Description Interaction-ID: 10048	drug/chemical compound Anakinra increases_activity of process insulin secretion in pancreas, in pancreatic islets
Drugbank entries	Show/Hide entries for Anakinra
Drugbank DB00026	Anakinra antagonist IL1R1

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