General Information:

Id: 1,387 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mammalia
BTO:0002181 HEK-293T cell; BTO:0000567 HeLa cell
article
Reference: Kim SH et al.(2009) Potentiation of amyotrophic lateral sclerosis (ALS)-associated TDP-43 aggregation by the proteasome-targeting factor, ubiquilin 1 J. Biol. Chem. 284: 8083-8092 [PMID: 19112176]

Interaction Information:

Comment It was suggested that UBQLN is a polyubiquitin-TDP-43 cochaperone that mediates the autophagosomal delivery and/or proteasome targeting of TDP-43 aggregates.
Formal Description
Interaction-ID: 9567

gene/protein

UBQLN1

affects_activity of

process

autophagy