General Information:

Id: 137 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mus musculus
article
Reference: Welsh GI et al.(1998) Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin. FEBS Lett. 421: 125-130 [PMID: 9468292]

Interaction Information:

Comment GSK3B phosphorylates eIF2B at Ser-540 and inhibits its activity.
Formal Description
Interaction-ID: 497

gene/protein

GSK3B

increases_phosphorylation of

gene/protein

EIF2B5

at Ser540
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