General Information:

Id: 1,371 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Homo sapiens
article
Reference: Vitte J et al.(2010) Leucine-rich repeat kinase 2 is associated with the endoplasmic reticulum in dopaminergic neurons and accumulates in the core of Lewy bodies in Parkinson disease J. Neuropathol. Exp. Neurol. 69: 959-972 [PMID: 20720502]

Interaction Information:

Comment Endogenous LRRK2 is colocalized with the endoplasmic reticulum markers Neurotrace and KDEL in human dopaminergic neurons. The finding of ER localization suggests the possibility that LRRK2 is involved in the ER stress response.
Formal Description
Interaction-ID: 9371

gene/protein

LRRK2

affects_activity of