General Information:

Id: 13,372
Diseases: Hematological
Homo sapiens
article
Reference: Ritchie H et al.(2001) Characterization of crosslinking sites in fibrinogen for plasminogen activator inhibitor 2 (PAI-2) Ann N Y Acad Sci 936: 215-218 [PMID: 11460477]

Interaction Information:

Comment PAI-2 remained active after cross-linking and inhibited fibrin breakdown, even by two-chain t-PA. Thus, a second inhibitor of fibrinolysis, in addition to alpha 2-antiplasmin, is crosslinked to fibrin and protects it from lysis.
Formal Description
Interaction-ID: 126037

gene/protein

SERPINB2

affects_activity of

process

fibrinolysis

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