General Information:

Id: 13,370
Diseases: Hematological
Mus musculus
article
Reference: Freeberg MAT et al.(2020) Transcriptomic Analysis of Cellular Pathways in Healing Flexor Tendons of Plasminogen Activator Inhibitor 1 (PAI-1/Serpine1) Null Mice J Orthop Res 38: 43-58 [PMID: 31424116]

Interaction Information:

Comment Injuries to flexor tendons can be complicated by fibrotic adhesions, which severely impair the function of the hand. Plasminogen activator inhibitor 1 (PAI-1/SERPINE1), a master suppressor of fibrinolysis and protease activity, is associated with adhesions.
Formal Description
Interaction-ID: 126033

gene/protein

SERPINE1

affects_activity of

process

fibrinolysis

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