General Information:

Id: 1,315 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
THP-1 monocytes
article
Reference: Wilkinson BL et al.(2012) Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimers disease Neurobiol. Aging 33: 197 [PMID: 20696495]

Interaction Information:

Comment S-ibuprofen disrupted downstream signaling to NOX2 (NADPH oxidase) complex assembly.
Formal Description
Interaction-ID: 9001

drug/chemical compound

Ibuprofen

decreases_activity of

process

signaling

signaling disruption to NOX2 (NADPH oxidase) complex assembly
Drugbank entries Show/Hide entries for Ibuprofen