General Information:
Id: | 1,311 (click here to show other Interactions for entry) |
Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance |
Mus musculus | |
male | |
ob/ob mouse | |
article | |
Reference: | Ozcan U et al.(2006) Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes Science 5790: 1137-1140 [PMID: 16931765] |
Interaction Information:
Comment | The authors found that administration of both PBA and TUDCA significantly suppressed hepatic glucose production (HGP) at baseline and during the clamp studies. |
Formal Description Interaction-ID: 8988 |
|
Comment | The authors found that administration of both PBA and TUDCA significantly suppressed hepatic glucose production (HGP) at baseline and during the clamp studies. |
Formal Description Interaction-ID: 8989 |
drug/chemical compound decreases_activity of process |