General Information:

Id: 1,309 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mus musculus
aged B6-R1.40 mice
Reference: Wilkinson BL et al.(2012) Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimers disease Neurobiol. Aging 33: 197 [PMID: 20696495]

Interaction Information:

Comment Ibuprofen inhibited fibrillar beta-amyloid-stimulated ROS production in primary microglia.
Formal Description
Interaction-ID: 8998

drug/chemical compound


decreases_quantity of

drug/chemical compound

Reactive oxygen species

in primary microglia; if ROS-production is stimulated by fibrillar amyloid beta peptides
Drugbank entries Show/Hide entries for Ibuprofen