General Information:

Id: 1,309 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mus musculus
aged B6-R1.40 mice
article
Reference: Wilkinson BL et al.(2012) Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimers disease Neurobiol. Aging 33: 197 [PMID: 20696495]

Interaction Information:

Comment A 9-month Ibuprofen treatment of aged R1.40 mice resulted in 90% decrease in plaque burden and a similar reduction in microglial activation.
Formal Description
Interaction-ID: 8942

drug/chemical compound

Ibuprofen

decreases_quantity of

Chronic ibuprofen treatment reduces AD-related plaque pathology in B6-R1.40 mice.
Drugbank entries Show/Hide entries for Ibuprofen