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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	1,299 (click here to show other Interactions for entry)
Diseases:	Diabetes mellitus, type II - [OMIM] Insulin resistance Obesity - [OMIM]
Organism:	Mus musculus
Gender:	male
Publication type:	article
Reference:	Ozcan U et al.(2004) Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes Science 306: 457-461 [PMID: 15486293]

Interaction Information:

Comment	Inositol-requiring kinase-1alpha (IRE-1alpha) plays a crucial role in insulin receptor signaling.
Formal Description Interaction-ID: 8910	gene/protein ERN1 affects_activity of process insulin receptor signaling pathway
Drugbank entries	Show/Hide entries for ERN1
Drugbank DB07382	N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclop ... not specified ERN1

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