General Information:

Id: 1,299 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mus musculus
male
article
Reference: Ozcan U et al.(2004) Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes Science 306: 457-461 [PMID: 15486293]

Interaction Information:

Comment Inositol-requiring kinase-1alpha (IRE-1alpha) plays a crucial role in insulin receptor signaling.
Formal Description
Interaction-ID: 8910

gene/protein

ERN1

affects_activity of

Drugbank entries Show/Hide entries for ERN1