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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	1,293 (click here to show other Interactions for entry)
Diseases:	Diabetes mellitus, type II - [OMIM] Insulin resistance
Organism:	Mus musculus
Publication type:	article
Reference:	Shi H et al.(2006) TLR4 links innate immunity and fatty acid-induced insulin resistance J. Clin. Invest. 11: 3015-3025 [PMID: 17053832]

Interaction Information:

Comment	TLR4 deficiency ameliorates impaired insulin signaling in muscle and reduced insulin-mediated glucose metabolism induced by lipid infusion.
Formal Description Interaction-ID: 8865	gene/protein TLR4 affects_activity of process insulin receptor signaling pathway in skeletal muscle
Drugbank entries	Show/Hide entries for TLR4
Drugbank DB02767	3-Hydroxy-Myristic Acid not specified TLR4
Drugbank DB08231	MYRISTIC ACID not specified TLR4

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