General Information:

Id: 1,293 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
Reference: Shi H et al.(2006) TLR4 links innate immunity and fatty acid-induced insulin resistance J. Clin. Invest. 11: 3015-3025 [PMID: 17053832]

Interaction Information:

Comment TLR4 deficiency ameliorates impaired insulin signaling in muscle and reduced insulin-mediated glucose metabolism induced by lipid infusion.
Formal Description
Interaction-ID: 8863

drug/chemical compound


decreases_activity of

in skeletal muscle; in wild-type