General Information:

Id: 1,276 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
SOD1G93A transgenic mouse, transfected with human SOD1G93A
BTO:0001279 spinal cord
Reference: Wu DC et al.(2006) The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice Proc. Natl. Acad. Sci. U.S.A. 103 [PMID: 16877542]

Interaction Information:

Comment NADPH oxidase caused formation of ROS (reactive oxygen species) and protein oxidation in transgenic SOD1G93A mice.
Formal Description
Interaction-ID: 8703


NADPH oxidase complex

increases_quantity of

drug/chemical compound

Reactive oxygen species

in spinal cord