General Information:

Id: 1,265 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Mus musculus
FVB mouse
BTO:0001311 corpus striatum
article
Reference: Chen X et al.(2008) Caffeine protects against MPTP-induced blood-brain barrier dysfunction in mouse striatum J. Neurochem. 4: 1147-1157 [PMID: 18808450]

Interaction Information:

Comment MPTP treatment decreased significantly the protein levels of both ZO-1 and occludin in striatum, and these effects were blocked by caffeine. Caffeine treatment alone had no effect on the protein levels of these two tight junction proteins.
Formal Description
Interaction-ID: 8590

drug/chemical compound

Caffeine

increases_quantity of

gene/protein

TJP1

in striatum; after MPTP treatment
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