General Information:

Id: 124 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Homo sapiens
BTO:0001279 spinal cord
article
Reference: Hetz C et al.(2009) XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy. Genes Dev. 23: 2294-2306 [PMID: 19762508]

Interaction Information:

Comment Human post-mortem spinal cord samples of sALS and fALS cases displayed a marked activation of both the UPR and autophagy.
Formal Description
Interaction-ID: 444

disease

Amyotrophic lateral sclerosis

affects_activity of