General Information:

Id: 1,232 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Fatty liver disease, nonalcoholic
Insulin resistance
Mus musculus
male
article
Reference: Mamane Y et al.(2009) The C3a anaphylatoxin receptor is a key mediator of insulin resistance and functions by modulating adipose tissue macrophage infiltration and activation Diabetes 58: 2006-2017 [PMID: 19581423]

Interaction Information:

Comment No significant difference in the expression of thermogenesis-related genes, uncoupling protein-1, and PPAR-gamma coactivator-1alpha in BAT was observed in wild-type and C3aR-/- mice.
Formal Description
Interaction-ID: 8404

gene/protein

C3AR1

NOT affects_expression of

gene/protein

PPARGC1A

in brown adipose tissue